1041066141ENSG00000142089ENSMUSG00000025492Q01628Q9CQW9NM_021034NM_025378NP_066362NP_079654Interferon-induced transmembrane protein 3 (IFITM3) is a protein that in humans is encoded by the IFITM3 gene.

[5][6][7] It plays a critical role in the immune system's defense against Swine Flu, where heightened levels of IFITM3 keep viral levels low, and the removal of IFITM3 allows the virus to multiply unchecked.

[8] This observation has been further advanced by a recent study from Paul Kellam's lab that shows that a single nucleotide polymorphism in the human IFITM3 gene purported to increase influenza susceptibility is overrepresented in people hospitalised with pandemic H1N1.

[9] The prevalence of this mutation is thought to be approximately 1/400 in European populations.

[9][10]