3MTC, 3N9V, 4CML, 5A7J, 5A7I363316330ENSG00000204084ENSMUSG00000028894P32019Q8K337NM_001297434NM_005540NM_001350227NM_001350228NM_008385NP_001352750NP_001352751NP_001352752NP_001352753NP_001352754NP_032411Type II inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5B gene.

[5][6] Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals.

The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases).

The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.

This article on a gene on human chromosome 1 is a stub.