The verse bar for "I Don't Know Anything" features a droning, overdriven guitar melody centered on the use of harmonics.

Although the single was released to radio across North America and the world, it was only commercially available in Austria.

"I Don't Know Anything" was first performed live at the band's October 12, 1994 concert in Seattle, Washington at the Crocodile Cafe.

A performance of the song is also included on the Live at the Moore home video release.

All songs written by Barrett Martin, Mike McCready, John Baker Saunders, and Layne Staley.