[1] He is a founding member of Critters Buggin, Garage a Trois, Ponga, Tuatara, and Skerik's Syncopated Taint Septet.

He has cited The Rolling Stones and Pink Floyd as bands from that time period who brought saxophone into rock music well.

In 2001 Skerik played the Pacific Northwest portion of Roger Waters' tour, reproducing the sax lead in "Money".

[10] Skerik is a founding member of Critters Buggin, Garage a Trois (which has included Stanton Moore, Charlie Hunter, Mike Dillon, and Marco Benevento), Crack Sabbath, and The Dead Kenny G's.

Skerik is an original member of Les Claypool's Fancy Band and Frog Brigade, Bobby Previte's Ponga and Coalition of the Willing and Joe Doria's McTuff.

Skerik has toured with Fred Wesley, Mike Clark and The Headhunters, Wayne Horvitz (Zony Mash), Mad Season and Roger Waters.

He has performed with Pearl Jam, Bonnie Raitt,[11] The Meters, Galactic, Dumpstaphunk, Johnny Vidacovich, Jacob Fred Jazz Odyssey, and Ween.