Goldberg began his Hollywood career in 2005 working on The WB series Related, starring Jennifer Esposito and Lizzy Caplan.

The writer gained notoriety in the summer of 2011, when he joined the ABC fantasy/drama Once Upon a Time,[1][2] writing and co-producing the show, which ran for seven years.

[4] On April 14, 2017, Goldberg and Andrew Chambliss were announced as joint showrunners for the 4th season of Fear the Walking Dead.

[10] Author Stephen King said of The Autopsy of Jane Doe that as "visceral horror, this terror tale rivals Alien and early Cronenberg.

"[11] In October 2019, Netflix began streaming the Paramount Players film Eli, directed by Ciaran Foy with a script by Goldberg, Naing, and David Chirchirillo.