[1][2][4] Other factors that contribute to iatrogenic anemia include bleeding from medical procedures and dilution of the blood by intravenous fluids.

[5] Iatrogenic anemia is of particular concern in intensive care medicine,[6]: 629  because people who are critically ill require frequent blood tests and have a higher risk of developing anemia due to lower hemoglobin levels and impaired production of red blood cells (erythropoesis) at baseline.

The average intensive care unit (ICU) patient loses up to 660 mL of blood per week to laboratory testing.

Infusion with large volumes of intravenous fluids dilutes the blood, causing a decreased hemoglobin and hematocrit level.

[2] People who develop iatrogenic anemia spend a longer amount of time in the hospital and have an increased risk of mortality.