A graduate with honours of the Gamal Abdel Nasser University of Conakry, in 1978 he joined the research department of the ministry of international cooperation as deputy director.

[1] In 1994 as minister without portfolio, he was general administrator in charge of major national projects and oversaw the restructuring of state-owned companies and the economic reforms necessary to shift the Guinean economy from a socialist to a liberal model.

In 2000 he left government for reasons said to include conflict with the army over its expenses,[4] and manipulation orchestrated against him by the entourage of President Lansana Conté.

In 2009, under the military transition after the death of President Lansana Conté, he returned to Conakry and created the Guinea for All party (GPT), which was notable in the Guinean political landscape for its categorical rejection of ethnic favoritism.

One of the 24 candidates in the first Guinean democratic presidential election of 2010, he presented a program focused on improving governance, decentralization and regional integration, ranking 11th in the first round with 0.66% of the vote.

[6] In the aftermath of the September 2013 legislative elections, where GPT obtained one seat out of 114, he re-established friendly relations with Alpha Condé who had asked for his help with the country's economic recovery.

[13] Prosecuted for Alleged acts of illicit enrichment and embezzlement of public funds, a warrant of committal was signed for Ibrahima Kassory Fofana's arrest, and he was detained at the Maison Centrale de Conakry prison on 6 April 2022 after three days of interrogation by the Court of repression of economic and financial offences (CRIEF).