Ignacio Agramonte y Loynaz (23 December 1841 – 11 May 1873) was a Cuban revolutionary, who played an important part in the Ten Years' War (1868–1878).

His father, also named Ignacio Agramonte, had been appointed by the Spanish Crown councillor of the Puerto del Príncipe City Council.

He returned to Puerto del Príncipe and married Amalia Simoni y Argilagos in August 1868, a woman who was the love of his life and whose family had considerably more wealth than his own.

When the war of independence against Spain broke out on October 10, 1868, he played a pivotal role in the uprising of Camagüey which took place on November 4, 1868.

He resigned his secretarial and ministerial position within the Congress after Carlos Manuel de Céspedes was made president that same year because Agramonte had strong political disagreements with him.

Showing vision, in spite of his lack of formal military training, his troops proved a huge challenge for the Spanish Army.

He personally led a furious charge, successfully rescuing Sanguily and routing the enemy troops, killing 11 and taking five prisoners.

The equestrian statue of Agramonte in the park that bears his name was unveiled by his widow Amalia Simoni in 1912; it was the work of an Italian sculptor.

His death in battle is the subject of the 1975 song "El Mayor" by Cuban nueva trova singer Silvio Rodríguez.