He was the first lithography docent at San Carlos Academy, where he also served as Principal.
[2] He was also alumnus of Claudio Linati, who was since 1826 the earliest lithographer of Mexico.
[2] In 1830, Serrano became the first lithography professor at San Carlos Academy.
[3] It was with this technique that he illustrated scientific, military, topographical, civic and musical texts.
[4] He also illustrated the Cacahuamilpa grottos and the Nevado de Toluca explorations in 1835.