From 1985 to 1986 he attended classes at the studio of prominent Moscow photographer, Alexander Lapin.

Mukhin is known for his photographs of Soviet rock musicians of the perestroika period,[4][5] including Viktor Tsoi, Boris Grebenshchikov, and Petr Mamonov.

Some of the photographs from these projects were shown at the Tretyakov gallery and La Maison Rouge in Paris in 2007.

[7][8] In 1999, Mukhin received a grant from the Paris Mayor's office to work on a project titled "Lovers in Paris" sponsored by FNAC (Fonds national d'art contemporain) and the French Committee to commemorate the year 2000.

His work has been published in many Russian magazines and in foreign editions such as Rolling Stone, GEO, Elle, Vogue, Le Monde, Libération, Esquire, and Time among others.