With the exception of some short-lived and thematic gazettes, the Nuovo Postiglione remained the only newspaper covering foreign affairs printed in Venice from 1741 to 1778.

Different headlines have been used during its publishing life, such as Novelle del Mondo (news of the world) or Compendio de' foglio più accreditati d'Europa (Summary of the most reliable papers of Europe).

In September 1781 the Nuovo Postiglione started to advertise other books of the same publisher, and it became issued two times a week, even if this change was formally authorized only in 1792.

[4] Giambattista Albrizzi remained the publisher until his death in 1777 (except from 1754 to 1758 when the newspaper was owned by the actual editor, Girolamo Zanetti).

[4] By order of the government of the Kingdom of Italy, in March 1812 the publications were interrupted along with all other newspapers in Venice, substituted by the Giornale dipartimentale dell'Adriatico published however always under the direction of Antonio Caminer.