[1] Delio is the founder of the Center for Christogenesis, an online educational resource for promoting the vision of Teilhard de Chardin and the integration of science and religion.

[4][5] After Delio entered the Franciscans, she enrolled at Rutgers University for a postdoctoral fellowship in neurotoxicology, where she researched heavy metal toxicity and nerve damage.

[9] Delio then accepted a post as a Senior Research Fellow at Georgetown University's Woodstock Theological Center, focusing on Science, Religion, and Technology.

[11] Delio speaks both nationally and internationally on topics such as quantum physics, artificial intelligence, evolution, and the importance and relevance of these fields for Christianity.

She has two books forthcoming, one on technology-mediated relationships in a post pandemic world, and another on Carl Jung, Teilhard de Chardin, and relational holism.