The Neu-Ulm–Kempten railway is a mostly single track and non-electrified main line from Neu-Ulm via Memmingen to Kempten in the German state of Bavaria.

Kempten citizens proposed a railway line to Ulm via Memmingen in 1843, as the construction of dams and water mills during the period of industrialisation had ended raft traffic on the river Iller and road transport was not viable.

It granted a concession on 13 September 1861 for the original 85 km (53 mi) long route that branched off the state railway from Neu-Ulm and ran up the river to Kempten.

[5][6] The RE 75 Regional-Express service runs hourly from Ulm to Kempten and Oberstdorf, using Pesa Link diesel multiple units.

Services on line RS 7 of the Danube-Iller Regional S-Bahn run from Ulm to Memmingen hourly.