The Illinois Central Railroad Yard, also known as Cherokee Illinois Central Station, is a nationally recognized historic district located in Cherokee, Iowa, United States.

The district was a collection of structures that were associated with the IC's second and third building phases, 1860 to 1870 and 1886 to 1888, and the expansion of the roundhouse in 1915.

It represented the last of the pre-Diesel era railroad yards left in Iowa.

The former depot is a 2+1⁄2-story brick structure on a limestone foundation, and capped with a hipped roof.

The American Express building is a single-story brick structure built on a concrete and limestone foundation.