Imam-Quli Khan (Persian: امام‌قلی خان, romanized: Emāmqolī Khān; died 1632) was an Iranian military and political leader of Georgian origin who served as a governor of Fars, Lar and Bahrain for the shahs Abbas I and Safi.

In 1619–20, Imam-Quli Khan oversaw Abbas's project to link the headwaters of the Karun and Zayandarud rivers in order to enhance the water supply of his capital, Isfahan.

[1][2] Being in charge of the Safavids' southern possessions, Imam-Quli Khan continued his father's policy of undermining the Portuguese positions in the Persian Gulf.

As a result, Imam-Quli Khan's army aided by the English navy captured the strategic Portuguese fort on the island of Qeshm and laid a siege to Hormuz, which surrendered after a defence of ten weeks on 22 April 1622.

This circumstance lasted until he and his two sons, one of them being Safiqoli Khan, were put to death at Safi's orders in late 1632,[6] while his vast possessions were converted into the crown domain in 1633.