Imiloxan

Imiloxan is a drug which is used in scientific research.

It acts as a selective antagonist for the α2B adrenergic receptor,[1] and has been useful for distinguishing the actions of the different α2 adrenergic subtypes.

[2][3] The imidazole portion of imiloxan is prepared by the reaction of an imidate with the diethyl acetal of aminoacetaldehyde.

N-Alkylation of the imidazole with ethyl iodide gives imiloxan.

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Imiloxan Synthesis: [ 4 ]