Founded in 1958, the club plays its home games at Estadio Banco Guayaquil, which opened in March 2021 and has a capacity for 12,000.

[4] Some well-known footballers the club has produced are Jefferson Montero, Junior Sornoza, Arturo Mina, Cristian Ramírez, Gonzalo Plata, Moisés Caicedo, Piero Hincapié, Willian Pacho and Kendry Páez .

After winning the Segunda Categoría in 2007, the club changed its name to Independiente del Valle and adopted the current colors (blue and black).

[6] Independiente del Valle unexpectedly reached the finals of the 2016 Copa Libertadores with incredible odds,[7] being compared to Leicester City's Premier League title that same year.

[8][5] Independiente began its knockout stage run by beating Copa Libertadores defending champions, Argentina's River Plate, in the round of 16 2–1 on aggregate.

[9] The club subsequently faced Argentina's giant Boca Juniors in the semi-final, defeating them 5–3 on aggregate, including a 3–2 victory at the famous La Bombonera stadium.

It was considered a major upset because Colón had a richer history and a much bigger fanbase, with around 40,000 fans at the stadium versus only 500 Ecuadorians.

The following players were chosen to represent their country at the FIFA World Cup while contracted to Independiente del Valle.