State Road 256 (SR 256) in the U.S. State of Indiana runs mostly through Scott and Jefferson counties, with short portions in Jackson and Washington counties.

SR 256 heads east from its western terminus toward Austin.

In Austin SR 256 has an interchange with Interstate 65 and then it has an intersection with U.S. Route 31.

After Austin SR 256 has an intersection with State Road 203.

Then SR 256 enters Jefferson County, where it has an intersection with State Road 3.