In 2020, the gallery's board voted to begin closing down operations, a result of financial strains caused by COVID-19.
[1] Founded in 2001 as a “museum without walls”, iMOCA mounted exhibitions around the city.
In 2004, the museum opened as a gallery in the historic Emelie Building in the Indiana Avenue Cultural District.
It continued to offer exhibits in The Alexander Hotel, Cat Head Press in the Englewood neighborhood, Indiana Landmarks, and the Hoosier Salon.
In 2018, it announced that it would open a permanent museum in summer 2019 in 2,300 square feet (210 m2) of the old Ford assembly plant at 1301 E. Washington Street on the city's near east side.