Indonesia competed at the 2012 Summer Paralympics in London, United Kingdom, from August 29 to September 9.

For its ninth participation in the Paralympic Games, the country fielded a delegation of four athletes in four different sports.

[2] Setiyo Budi Hartanto (a left forearm amputee) competed in the men's long jump and triple jump F46 (a category for athletes with disabilities affecting the upper limbs or the torso).

[2] Agus Ngaimin (who is paralysed from the waist down) competed in the men's 100m backstroke S6.

[2] David Jacobs competed in the men's singles, class 10 (a category for standing players with a comparatively low level of disability).