Infection and Immunity is a peer-reviewed medical journal published by the American Society for Microbiology.

Areas covered include molecular pathogenesis, cellular microbiology, bacterial infection, host responses and inflammation, fungal and parasitic infections, microbial immunity and vaccines, and molecular genomics.

Through its "Global Outreach Program," free online access is available to qualified microbiologists in eligible developing countries.

Prior to that time, original research articles covering topics in infection and immunity were published in a section of the Journal of Bacteriology.

As the size of this section grew, the need for a separate journal publishing peer-reviewed research in this area became apparent.