In human anatomy, the infraorbital foramen is one of two small holes in the skull's upper jawbone (maxillary bone), located below the eye socket and to the left and right of the nose.

In anatomical terms, it is located below the infraorbital margin of the orbit.

The ramifications of the three principal branches of the trigeminal nerve—at the supraorbital, infraorbital, and mental foramen—are distributed on a vertical line (in anterior view) passing through the middle of the pupil.

[2] Palpation of the infraorbital foramen during an extraoral examination or an administration of a local anesthetic agent will cause soreness to the area.

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