It is located posterior to the maxilla, between the lateral pterygoid plate of the sphenoid bone medially and by the base of skull superiorly.
[2] The term is derived from infra- meaning below and temporal which refers to the temporalis muscle.
They may be significant however, as it is possible for infection to spread via emissary veins from the pterygoid plexus to the cavernous sinus, which may result in cavernous sinus thrombosis, a rare but life-threatening condition.
[2] The signs and symptoms of an infratemporal space infection are swelling of the face in the region of the sigmoid notch, swelling of the mouth in the region of the maxillary tuberosity and marked trismus (difficulty opening the mouth), since some of the muscles of mastication are restricted by the swelling.
[2] The spread of odontogenic infections may sometimes involve the infratemporal space.