Upon reaching Earth, she arranged a deal with Lex Luthor for his help in colonizing the planet and converting LexCorp moonbase workers into drones.

[5] Following her work on the moonbase, she returns to Earth to help Luthor fulfill her end of their deal, only to learn Lana Lang took his place as CEO of LexCorp.

Insect Queen kidnaps her and takes her to the moonbase, where she metamorphoses into a form combining Lang's appearance with her insectoid features.

After capturing Superman during his attempt to rescue Lang, she uses her midges on him to enhance her psychic powers and uses his genetic template to create "super soldier-ants".

Nonetheless, Supergirl breaks free and uses Kryptonian technology to help Lang expel the Insect Queen, restoring the former.