The fifteenth season of Family Guy aired on Fox in the United States from September 25, 2016, to May 21, 2017.

The executive producers for the fifteenth production season are Seth MacFarlane, Richard Appel, Steve Callaghan, Danny Smith and Kara Vallow.

Guest stars for the season include Kyle Chandler, Stephen Curry, Flea, Rob Gronkowski, Sean Penn, Frank Sinatra Jr., David Tennant, and Jacob Tremblay.

Other episode plots include Brian and Stewie writing songs for kids ("The Boys in the Band"), Chris becoming a star baseball player ("Bookie of the Year"), Rob Gronkowski moving in next to Peter with his party bus ("Gronkowsbees"), a homage to three novels commonly taught in (and, in some cases, banned from) American high school English classes ("High School English"),[1][4] Peter and Lois joining the anti-vaccination movement ("Hot Shots"),[5] Peter meeting the children he never knew he had ("A House Full of Peters"), Chris falling for a Mexican teen mom ("Dearly Deported"), and a fictionalized behind-the-scenes look of the show ("Inside Family Guy").

When Chris starts showing signs of aggression, Peter and Lois end up discovering that he is a talented baseball pitcher.