The institute is the Egyptian church's main research centre in subjects of Coptology and for shared in many research about different aspect of Coptology since its establishment.
The Coptic painters Isaac Fanous and Adel Nassief studied in the institute.
One of the teachers was Mikhail Girgis El Batanouny, the Coptic music expert.
The institute was mainly founded by its first president Professor Aziz Suryal Atiya who was also the Founder of the Middle East center, University of Utah.
[2] Other prominent Coptologists and Egyptologists contributed to its establishment as Professor Dr Pahor Labib Director of the Coptic Museum in Old Cairo (1951–1965).