This disease is often caused by brain trauma, producing medial ventral lesions to the extrastriate cortex.
[2] Symptoms generally include memory or learning impairments, with the inability to integrate parts coherently.
[2] Some of the causes of integrative agnosia include stroke, traumatic brain injury, Alzheimer's disease, an anoxic episode following myocardial infarction, and progressive multifocal leukoencephalopathy.
Those who have integrative agnosia are better able to identify inanimate than animate items, which indicates processes that lead to accurate perceptual organization of visual information can be impaired.
[1] Although the grouping of local elements into perceptual wholes can be impaired, patients can remain sensitive to holistic visual representations.
The key factor for this type of treatment to be successful is a regular and consistent exposure, which will lead to improvements in the long run.
In the fourth and final section of experiments, the patient shows a lack of visual color knowledge, but structures of a given specific object is not impaired, as H.J.A.
This shows that the patient's visual perceptions and memories containing prior knowledge are not altered by integrative agnosia following the stroke.
In the first group of experiments, Riddoch and Humphreys tested the patient's visual, spatial, and perceptual capabilities.
His results showed that patients with integrative agnosia have problems in accurately recalling spatial information from long-term memory.
The evidence of his inability to assess the spatial distances supported the correct diagnosis of integrative agnosia.
In the second group of experiments, the patient, H.J.A, was tested on his ability to manipulate images, assess information using his spatial memory, and complete pattern tasks.
The tasks that H.J.A were given showed where the parts specifically failed to integrate: the patent's perception on spatial elements without a point of reference.
In contrast, impairment was gauged to be the lack of the ability in recalling spatial layouts, judging spatial directions, judging relative positions of objects, The Brooks Matrix Test, Compass Direction Task, reproducing abstract patterns, and reproducing both possible and impossible figures.
Due to the impairment, it was identified that the patient did not have intact imagery and visual short-term memory, made apparent by the spatial relations test.
Due to Integrative Agnosia, the patients take information from a top-down manner, using stored knowledge to retrieve an objects perceptual properties.