The eighth Inter-Cities Fairs Cup was played over the 1965–66 season.

The competition was won by Barcelona over two legs in an all-Spanish final against Zaragoza.

It was the sixth and final time that a Spanish side won the competition, and Barcelona's third title.

RC Strasbourg 2–2 Milan on aggregate; play-off needed.

Valencia 2–2 Hibernian on aggregate; play-off needed.

Chelsea – Barcelona 2–2 on aggregate, replay is needed.