Designed by Dinu Hariton, Gheorghe Nădrag, Ion Moscu, and Romeo Belea, the hotel was part of a larger development that included the Bucharest National Theatre.

During the Romanian Revolution of 1989, the balconies of the Inter-Continental were used to report on the protests in the adjacent University Square.

The hotel was renamed slightly in 2003, becoming the InterContinental Bucharest, when the chain was reorganized and dropped the hyphen from its name.

The apartment contains white Italian walnut furniture polished with gold and Murano glass light fixtures.

In its living room there is a fully functioning Steinway & Sons white piano which was specially brought in for Nigel Kennedy's stay at the hotel in winter 2007.