After traversing Brooklyn and crossing the Cuyahoga River on the Valley View Bridge, the highway continues east toward the communities of Bedford and Twinsburg toward its eastern terminus at I-80 and the Ohio Turnpike in Streetsboro.

Due to the convergence of these high traffic roads, congestion is common during peak times.

[citation needed] I-480 was conceived as a means of giving motorists a faster way of crossing Cleveland's southern borders and suburbs.

[13] Construction from west to east began as political controversies and engineering work were resolved on the highway's middle section.

[14] The two miles (3.2 km) of the route north and northeast of Cleveland Hopkins International Airport proved the most difficult to plan due to existing high levels of traffic on Brookpark Road and the expansion requirements of the airport.

[10] The final $115-million (equivalent to $296 million in 2023[6]),[15] 2.5-mile (4.0 km) segment linking the east and west ends of I-480 was finished in August 1987.