The freeway begins northeast of the middle of the World Trade International Bridge in Laredo and ends at I-35.

The Federal Highway Administration (FHWA) approved the designation of a 1.4-mile (2.3 km) section of freeway in Laredo as part of I-69W.

[1] When extended, I-69W will follow US 59 serving Freer, George West, and Beeville before terminating with I-69E and both interstates meeting I-69 in Victoria.

The Intermodal Surface Transportation Efficiency Act of 1991 included two High Priority Corridors that would later become parts of a proposed cross-country extension of I-69: The National Highway System Designation Act of 1995 made further amendments to the description of Corridor 18, specifying that it would serve Mississippi and Arkansas, extending it south to the Mexico–U.S.

[10] Projects to extend the Interstate to the Duval–McMullen county line are currently in the planning stage but not completely funded.

[11][12] The US 59 bridge over the San Antonio River is planned to be replaced, it was funded by the Infrastructure Investment and Jobs Act.