After attending Unirea High School in Focșani, he pursued his studies at the University of Bucharest, taking courses at the Faculty of Letters and Philosophy, Department of Classical Philology.
Because of his stay in Berlin he also got acquainted with some materials preserved kept at the Museum of Archeology, at the prehistoric section, coming from the Romanian territory, collected in the previous decades.
Thus, on February 13, 1934, Nestor, assistant at the National Museum of Antiquities, informed the leadership of the Ministry of Instruction, Cults and Arts that he published in Berlin, under the auspices of the German Archaeological Institute, a synthesis of Romanian prehistory.
From 1945 he carried out at the same time a prestigious didactic career as a professor at the University of Bucharest, contributing to the formation of disciples (such as noted archaeologist Alexandru Vulpe) who, through what they achieved, proved that they properly received what was invested by their mentor, Ion Nestor.
Through the studies undertaken, Ion Nestor contributed to the substantiation of the formation process of the Romanian people, constituting at the same time a valuable methodological guide for the younger collaborators through the way of analysis, synthesis, and support of the stated theses.
As a trainer for future researchers, Ion Nestor has paid a lot of attention to the way of stating the findings by each of participant on the site, intervening, when he considered it necessary, with connections that allowed a clarification of the problem in question.