[1] She became the Queen consort of Syrian King Sampsiceramus II of Emesa.
She was most probably born, raised and educated in Samosata, the capital of the Kingdom of Commagene.
Iotapa married King Sampsiceramus II from the Royal family of Emesa, Syria.
[2] Her daughter Iotapa would marry Aristobulus, while her sons would become kings of Emesa.
[2] From a surviving inscription dated from the reign of her husband, Sampsiceramus II along with Iotapa are known as a happy couple.