The combination of Mifune's unified art style and large range of illustrations has contributed to Irasutoya's popularity and prevalence.

[7] A Twitter trend to recreate the cover art of albums, video games, manga, and light novels using illustrations from Irasutoya occurred in 2016.

[2][12] In addition to typical clip art topics, unusual occupations such as nosmiologists, airport bird patrollers, and foresters are depicted, as are special machines like miso soup dispensers, centrifuges, transmission electron microscopes, obscure musical instruments (didgeridoo, zampoña, cor anglais), dinosaurs and other ancient creatures such as Hallucigenia and Pikaia, and subjects from fantasy and games (Hero, Mi-Go, Buer), many of which are rare in the free culture world.

Other topics include Japan Self-Defense Forces personnel, politics, covert photography via hidden cameras and smartphones, gaming mice, education, wisdom teeth, chūnibyō teenagers, depictions of bipedal and quadrupedal chupacabras, and the Antikythera mechanism.

[16][17][18] In March 2016, Mifune announced the temporary cessation of current affairs illustrations, with the sentiment that if he continued, Irasutoya would become less like a hobby and more like a job.

[21] That same year, in collaboration with I'm Standing on a Million Lives, serialised in Bessatsu Shōnen Magazine, a special "Wakeari Free Edition" in which all panels from the latest five volumes were replaced with Irasutoya material was published for free on Kodansha's "Magamega" website and in Weekly Shōnen Magazine.

[22] Alongside the first episode of I'm Standing on a Million Lives's first anime season, the "Wakeari Version" was broadcast in October 2020.