Lady Irene Drusilla Namaganda (November 11, 1896 – September 15, 1957) was the first woman to have the title of Nnabagerekka (queen consort) of the kingdom of Buganda.

She attended Gayaza High School, created by the Church Missionary Society to educate the children of Buganda's elites.

Despite the intent that their marriage be a Christian one intended to showcase Buganda's adoption of Anglicanism, Daudi Chwa accumulated sixteen other wives and fathered 36 children.

Namaganda soon began a relationship with Simoni Petero Kigozi, a school teacher nineteen years younger than her.

The political scandal that erupted resulted in a series of court cases from 1941 and 1943, culminating in the exile of the couple from the capital of Buganda, the resignation of Prime Minister Martin Luther Nsibirwa, and Namaganda's deposition as Nnamasole in favor of her elder sister Perepetwa Nnaabawesi Kaidzi.