Irene Komnene Laskarina Branaina (Greek: Ειρήνη Κομνηνή Λασκαρίνα Βρανᾶίνα; died around 1271) was a Byzantine noblewoman and wife of sebastokrator Constantine Palaiologos, half-brother of Byzantine Emperor Michael VIII Palaiologos.
She seems to have followed suit after her husband's retirement to a convent, and taken the monastic name of Maria.
She probably died as a nun.
Irene was the granddaughter of Byzantine General Theodore Branas and Agnes of France,[1] though the Branas genealogy is poorly recorded.
Irene was married c. 1259/60 to Constantine Palaiologos,[2] by whom he seems to have had five children"[citation needed]