She gained popularity for her film song, "Tumhi ho mehboob mere" for movie Aaina (1966).
[1] In the beginning, Irene used to sing in Radio Pakistan's music programs.
She sang some popular duets with Masood Rana and Ahmed Rushdi.
She later sang many hit songs for 31 films including one super-hit song in film Aina (1966), Tum Hee Ho Mehboob Meray, with lyrics by Khawaja Pervez and music by M Ashraf.
[1][3] Irene married Cecil Samuel, a man from a prominent Peshawari family.