She may be the same Irene Syrikaina whom Michael Panaretos mentions was stoned to death in September 1332 in the purges that followed Basil Megas Komnenos's accession to the throne.
[2] The name may be related to the island Syros or to the terms "Syrios", "Syrikos", "Syriakos", all Greek language for Syrian.
[3] Irene is briefly mentioned in the chronicle of Michael Panaretos: "And the son of lord Manuel by the lady Irene Syrikaina, the lord George Komnenos, succeeded to the throne and reigned for fourteen years"[4] This indicates that she was the mother of George, Emperor of Trebizond and John II of Trebizond, presumed to have been the youngest sons of Manuel.
According to "The Bagrationi (Bagration) Dynasty" by Christopher Buyers, the Didebul were "non-hereditary noblemen of high rank, senior to aznaur, usually enjoyed by one in state service".
[4] Based on a passage in the Georgian "Annals of Sebastian", Anthony Bryer has argued that Irene Syrikaina played a role in the deposition of her son George (who became Emperor in 1266 on the death of his half brother Andronikos), and thus was still alive June 1280.