Besides Kane, it had distinguished editors like Robert James Graves and William Wilde.

[1] It is the official organ of the Royal Academy of Medicine in Ireland and published by Springer Science+Business Media.

Contributors included Dublin physicians Abraham Colles (1773–1840), William Stokes (1763–1845), Sir Philip Crampton (1777–1858), Thomas Ledwich (1823–1858), Arthur Jacob (1790–1874), Robert Adams (1791–1875), Stephen Myles MacSwiney (died 1890), Sir Charles Cameron (1830–1921) and Ephraim MacDowel Cosgrave (1847–1925).

James Little (1837–1916) was editor from 1869 to 1875; during his tenure, the journal changed from a quarterly to a monthly publication.

[3] The journal is abstracted and indexed in Academic OneFile, Chemical Abstracts Service, CSA, Current Contents/Clinical Medicine, EMBASE, Health Reference Center Academic, IBIDS, INIS Atomindex, PubMed/MEDLINE, Science Citation Index Expanded, Scopus, and Summon by Serial Solutions.