U.S. Route 52 passes through the village, leading south 4 miles (6 km) to Sheldon and northwest the same distance to Donovan.
The Indiana border is 3 miles (5 km) to the east via County Highway 31.
According to the 2021 census gazetteer files, Iroquois has a total area of 0.57 square miles (1.48 km2), all land.
There were 81 housing units at an average density of 142.86 per square mile (55.16/km2).
28.32% of all households were made up of individuals, and 8.85% had someone living alone who was 65 years of age or older.