Its major tributary is Chalippuzha, which joins with it about 3 km north of Thiruvambady town.

The villages of Anakkampoyil, kandappanchal,Narangathode,Thiruvambady, Mukkam, Kodiyathur, Chennamangallur and Cheruvadi are on the banks of this river.

Naadan Premam (transl: Love in the Countryside), a major romantic novel by Malayalam writer S. K. Pottekkatt, is set in the backdrops of Iruvanjippuzha.

The river is also mentioned in the film Ennu Ninte Moideen.

In this film it shows how the real character dies B. P. Moideen after drowning in the Iruvanjippuzha River.