Isa Abdul-Quddus (born August 3, 1989) is a former American football safety.

He was signed by the New Orleans Saints as an undrafted free agent in 2011 and also played for the Detroit Lions and Miami Dolphins.

Abdul-Quddus was signed by the New Orleans Saints as an undrafted rookie free agent following the 2011 NFL draft.

[3] On March 9, 2016, the Miami Dolphins signed Abdul-Quddus to a three-year contract totaling $12.75 million.

He was placed on injured reserve on December 28, 2016, after suffering a neck injury in Week 16 against the Buffalo Bills.