Isaac Fitzgerald Shepard (July 7, 1816 – August 25, 1899) was a colonel in the Union Army during the American Civil War.

His appointment as a brigadier general of volunteers was not confirmed by the United States Senate and expired on July 4, 1864.

[1][3] As a colonel he led the African Brigade, XVII Corps, Army of the Tennessee, during the Siege of Vicksburg.

[1][3] He was stationed at Vicksburg, Mississippi, with a brigade of three regiments of United States Colored Troops.

[1] The United States Senate did not confirm his appointment as brigadier general and it expired on July 4, 1864.