Isaac Stiles Hopkins (June 20, 1841 – February 3, 1914) was a professor and the first President of the Georgia Institute of Technology (1888–1896) as well as pastor of the First Methodist Church in Atlanta, Georgia.

He returned to Emory to teach natural science, and then physics at Birmingham-Southern College (then known as Southern University), before returning to Emory and becoming vice president in 1882 and president in 1885.

Hopkins resigned from Georgia Tech in 1896 to serve the church full-time.

[5] One of the two pillars comprising the Haygood-Hopkins Memorial Gateway, informally known as Emory University's "front door," is named for Hopkins.

The pillar's inscription says of Hopkins, "A pioneer in technical education, he was one of the builders of the New South."