[1] In the 1850s Kalloch served as a Baptist minister in Rockland, Maine and then Boston, Massachusetts at Tremont Temple from 1855 to 1860, where he was acquitted of accusations of adultery in 1857.

[3] In 1878, Kalloch became one of the major religious leaders of San Francisco to endorse the Workingmen's Party of California.

This endorsement brought himself increased fame as "workingmen flocked to his church" and his "halls were packed as never before."

[4] During Isaac Kalloch's campaign for mayor, he came under attack from the San Francisco Chronicle's editor-in-chief, Charles de Young, who was backing another candidate.

De Young, with the hopes of taking Kalloch out of the mayoral race, accused the minister of having an affair.