[1][2] After high school, Yiadom signed with Boston College over offers from Bryant, Holy Cross, and Connecticut.

[5] Prior to the Senior Bowl, Yiadom was ranked as the 47th best cornerback prospect in the by DraftScout.com and was unheralded due to his minimal targets in college.

He impressed scouts and analysts with a strong week of practice for the Senior Bowl and immensely helped his draft stock.

At the conclusion of the pre-draft process, Yiadom was projected to be a third or fourth round pick by NFL draft experts and scouts.

He committed a pass interference penalty on the opponent's opening drive to set up a Bears touchdown.

[17] On January 21, 2022, he was released along with Jack Heflin to open roster spaces for the returns of Za'Darius Smith and Whitney Mercilus from injured reserve prior to the divisional playoff game.