She teaches courses on European fascism, World War I, German history 1648–present, and international law.
In 2014, Hull published A Scrap of Paper: Breaking and Making International Law During the Great War, analyzing the Allied blockade of Germany.
The book was criticized by other historians for failing "to take considerations of morality and, perhaps more importantly, legitimacy [of the blockade] into account".
[1][2] Michael Geyer of the University of Chicago has stated that "Isabel V. Hull is one of the most accomplished German historians and surely the best of her generation," and she has been described by VICE News as "one of America's leading scholars on the role of fascism in history.
In 2013, she was awarded the inaugural International Research Support Prize by the Max Weber Stiftung and the Historisches Kolleg.