She appeared in United Kingdom sources in 1802 and between 1802 and 1810 she made nine annual voyages as a whaler in the northern whale fishery (Davis Strait (DS) and Greenland (Gr)).

When Isabella returned home to Newcastle in 1808 one of her crewmen lost his arm.

The arm was shot off when he fired a cannon to signal her arrival.

[2] On 17 December 1808 HMS Briseis towed Isabella, of Newcastle, Lambert, master, into Harwich.

[3] Isabella was last listed in the Register of Shipping in 1813, with data unchanged since 1810.