She made one voyage transporting convicts from Mauritius to Australia.

Isabella appears in the Register of Shipping with Maughan as master and owner, and with trade London to Hamburg.

[1] Isabella, under the command of George Maughan left Cowes, Isle of Wight on 21 February 1833 with a general cargo and arrived at Cockburn Sound, Western Australia, on 24 July 1833.

[4] Isabella sailed from Sydney for London, under the command of Captain Ryan, on 6 March 1838, with passengers and cargo.

[5] A "piratical brig" under a Spanish flag boarded her on 4 July and took a new main-top-sail, a cask of beef, and various other articles.