As one of the few contestants to represent their actual state of origin, Ayuk was the first South-South woman to win the title since Celia Bissong in 2003.
VMMF was committed to the protection of rural dwellers against the spread of typhoid fever, malaria, HIV\AIDS, tuberculosis and other opportunistic infections.
Under IAF, one of her particular philanthropic acts that swept the internet was in 2018 when going after the aid of a certain widow who was thrown out of her home by the children of her late husband, despite being an ex- beauty queen Ayuk was said to have travelled the remotest part of Cross River even sailing by boat at some points to Bendeghe-Afi community, where the widow resides.
In 2019, the former MBGN Queen, provided free cervical cancer public and preventive education, Screening & Diagnosis services to underserved women in Cross River State through her foundation.
On February 27, 2013, in Abuja, Nigeria's capital Ayuk launched her new fashion brand called Bellesabel, a coinage she made from combining the French word belle meaning beauty, and Sabel, a shortening of her name Isabella.
[16] On her 27 birthday in 2013 at Clay Night club, Abuja, in a telephone interview with Obaji Akpet of the Nation Newspaper Ayuk announced plans to feature in a movie, Alok Monument, the pride within.